Northwestern State (9-10) comes into the series after being swept by Texas Christian in a two-game set on Tuesday and Wednesday. Oklahoma (14-4) will enter the series after sweeping New Mexico State 8-0 and 3-2.
The Demons will start Robert Baker (2-0, 2.52 ERA) on the mound for the Friday matchup. Baker threw nine innings in his last outing on his way to a no decision; NSU dropped the game against Louisiana-Monroe in 10 innings.
The Sooners will put Jonathan Gray (3-1, 2.03) on the mound for the series-opener.
Matt Oberste, who has a .448 batting average with 30 hits and 25 runs batted in, leads OU at the plate. He has six doubles, two triples, and five home runs.
He is the only batter in the Sooner lineup that hits over .300, but Max White, Kolbey Carpenter, Hector Lorenzana, and Garrett Carey all hit .280 or above.
Will Watson (.362) and Cort Brinson (.302) leads NSU in hitting. Watson has 13 runs batted in and Brinson is tied for third on the team in RBI with eight. Nick Purdy and Todd Wallace each have eight, right behind Matt Baca with nine.
Saturday's game will start 2:00, and Sunday's will be played at 1 o'clock.
After this three-game set, the Demons will play a single, midweek game at LSU and then return home to open Southland Conference play with Southeastern Louisiana.
Oklahoma began Week 5 of the 2013 season ranked No. 17 by USA Today, No. 19 by Collegiate Baseball, No. 20 by the NCBWA, No. 21 by Perfect Game and No. 23 by Baseball America.
Oklahoma hosts Oral Roberts next Tuesday and Wednesday before opening its 2013 Big 12 Conference slate against TCU next weekend.
The Demons took the series opener, 13-10, in 12 innings but the Sooners bounced back by winning the final two contests by scores of 15-8 and 7-6.